Her research interest is in the area of labor economics and public policy. Afxentiou has made contributions that impact on the academic community in the area of Teenage Pregnancy and Wage Polarization through papers published in competitive journals in this domain space (e.g. Journal of Family and Economic Issues, Journal of Business and Economic Studies). She has also made contributions through service to the academic community, as recognition of her scholarship, through her inclusion as a reviewer and discussant for several academic conferences (e.g. Academy of International Business / Multinational Finance Society).